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Published on Jan 22, 2025

FrieslandCampina Ingredients announce GRAS status for Vivinal Lactoferrin product

A recent press release from FrieslandCampina Ingredients announced that the company's Vivinal Lactoferrin ingredient received Generally Recognized as Safe (GRAS) status for utilization in “cow’s milk-based non-exempt infant formula for term infants and …

Source: Nutritional Outlook - Neutral
Published on Jan 22, 2025

Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells

Mammalian cochlear hair cells (HCs) comprise a single row of inner hair cells (IHCs) and three rows of outer hair cells (OHCs). HCs transduce sound-mediated mechanical force into neural electrical codes for ear-brain intercommunication. The IHCs are the …

Source: eLife - Label Pending
Published on Jan 21, 2025

Active Ingredients and Potential Mechanism of Additive Sishen Decoction in Treating Rheumatoid Arthritis with Network ...

Introduction Rheumatoid arthritis (RA), a chronic inflammatory autoimmune disease that affects approximately 1% of the population worldwide, is characterized by painful, swollen joints that can severely impair physical function and quality of life.1,2 The …

Source: Dove Medical Press - Neutral
Published on Jan 22, 2025

Non-Small Cell Lung Cancer Pipeline, Clinical Trials, Emerging Drugs Approvals and Companies | DelveInsight

Non-Small Cell Lung Cancer Pipeline LAS VEGAS, NV, UNITED STATES, January 22, 2025 /⁨EINPresswire.com⁩/ -- DelveInsight’s, Non-Small-Cell Lung cancer (NSCLC) Pipeline Insight” report provides comprehensive insights about 100+ companies and 120+ …

Distribution channels: Healthcare & Pharmaceuticals Industry ...
Published on Jan 16, 2025

Membrane mimetic thermal proteome profiling (MM-TPP) towards mapping membrane protein-ligand dynamics

Integral membrane proteins (IMPs) are essential to numerous cellular functions, including signal transduction, cell-cell recognition, and the transport of nutrients and ions across cellular membranes (Boulos et al., 2023). Although comprising only 20 to …

Source: eLife - Label Pending
Published on Jan 16, 2025

Integrated Network Pharmacology, Machine Learning and Experimental Validation to Identify the Key Targets and Compounds ...

Introduction Breast cancer, a life-threatening disease with limited therapeutic potential, ranks among the most prevalent malignant tumors affecting women and is the most frequently diagnosed cancer, as well as the leading cause of cancer-related mortality …

Source: Dove Medical Press - Neutral
Published on Jul 31, 2024

Notable 2024 FDA decisions

When it comes to innovative new treatments, 2023 was a tough act to follow. Novel drug approvals reached an all-time high last year, with the U.S. FDA greenlighting 55 new drugs, more than half of which targeted rare disease. 2023 was also a breakthrough …

Source: Pharma Manufacturing - Label Pending
Published on Jan 22, 2025

Chronic Stress Mediates Inflammatory Cytokines Alterations and Its Role in Tumorigenesis

Introduction Numerous studies have demonstrated that chronic stress is a significant risk factor for cancer, contributing to its initiation, progression, and metastasis.1,2 Chronic stress mediates the release of pro-inflammatory cytokines, such as …

Source: Dove Medical Press - Neutral
Published on Jan 22, 2025

A Multifunctional MIL-101-NH2(Fe) Nanoplatform for Synergistic Melanoma Therapy

Introduction Malignant melanoma is characterized by its high aggressiveness and resistance to therapy, representing the leading cause of death among skin cancer patients.1,2 Currently, the predominant modality for melanoma treatment involves surgical …

Source: Dove Medical Press - Neutral
Published on Jan 21, 2025

Sonnet BioTherapeutics Expands Phase 1 SB101 Trial to Evaluate Combination of SON-1010 with Trabectedin in Certain ...

SON-1010, after receipt of data suggesting clinical benefit when administered as a monotherapy in patients with advanced solid tumors, enters combination evaluation with trabectedin (Yondelis®) with the potential to improve trabectedin’s therapeutic window …

Distribution channels: Technology ...
Published on Jan 21, 2025

Neutrophils: From Inflammatory Bowel Disease to Colitis-Associated Colorectal Cancer

Introduction Inflammatory bowel disease (IBD) is a non-specific inflammatory disease of the digestive tract, primarily manifesting as ulcerative colitis (UC) and Crohn’s disease (CD). Despite significant advancements in medical science and clinical …

Source: Dove Medical Press - Neutral
Published on Jan 20, 2025

iRGD-Targeted Biosynthetic Nanobubbles for Ultrasound Molecular Imaging of Osteosarcoma

Introduction Osteosarcoma, characterized by a high degree of malignancy, strong invasiveness, rapid disease progression, and extremely high mortality rate, is the most common primary malignant tumor of the bone. It accounts for approximately 20% of all …

Source: Dove Medical Press - Neutral
Published on Jan 16, 2025

Obstacles and innovations of macrocyclic drug development

Macrocycles outperform traditional therapeutics on several fronts, yet they account for just four percent of FDA-approved drugs. Colleagues Ann E Cleves and Ajay N Jain from Optibrium Ltd explain why we can expect to see this number increase in the coming …

Source: Drug Target Review - Neutral
Published on Jan 16, 2025

Ten first-in-class drugs on track for FDA approval in 2025

Newsletter Signup - Under Article / In Page "*" indicates required fields First-in-class drugs are therapies that utilize novel mechanisms of action, offering new approaches to challenging diseases. In 2024, the U.S. Food and Drug …

Source: Labiotech - Neutral
Published on Jan 17, 2025

Utility of 131I-HLX58-Der for the Precision Treatment: Evaluation of a Preclinical Radio-Antibody-Drug-Conjugate ...

Introduction Gastric cancer (GC) ranks as the fifth most common malignant tumor and the fourth leading cause of cancer-associated deaths worldwide.1,2 Notably, the incidence of gastric cancer among young adults (aged < 50 years) has progressively …

Source: Dove Medical Press - Neutral

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Published on January 23, 2025 - 05:28 GMT

3-Time Inc. 500 Award-Winning Entrepreneur Jon Flatt Expands Business Accelerator The Guardian CEO to Louisiana

LAFAYETTE, LA, UNITED STATES, January 23, 2025 /⁨EINPresswire.com⁩/ -- Jon Flatt, a Lafayette native and accomplished entrepreneur, is pleased to announce he is bringing his latest business venture, The Guardian CEO, to Louisiana. Flatt is …

Distribution channels: Banking, Finance & Investment Industry, Business & Economy ...
Published on January 23, 2025 - 05:26 GMT

The Guardian CEO Supports Startups in Achieving $50M Valuations Led by Three-Time Inc. 500 Winner Jon Flatt

AUSTIN, TX, UNITED STATES, January 23, 2025 /⁨EINPresswire.com⁩/ -- The Guardian CEO, a business accelerator led by Jon Flatt, a three-time Inc. 500 and two-time Lumiere Award-winning CEO, is pleased to announce it is providing startups and small …

Distribution channels: Banking, Finance & Investment Industry, Business & Economy ...

Published on January 22, 2025 - 16:24 GMT

Flexdev Group expands to the USA with acquisition of The Emblem Source, a leading sports textile customization company

Flexdev Group, Europe's No. 1 textile customization company for sport acquires The Emblem Source, the US leader in sports badges and patches. MACCLESFIELD, UNITED KINGDOM, January 22, 2025 /⁨EINPresswire.com⁩/ -- • Flexdev Group, Europe's …

Distribution channels: Companies, Manufacturing ...
Published on January 22, 2025 - 19:43 GMT

Unrattled Company Announces The Winglet Is Here: Now In Stock Along with Exciting Add-On Items

The Winglet is here! The revolutionary all-in-one solution for traveling with lap infants—designed for feeding, resting, playing, and sitting—is now in stock! HENDERSON, NV, UNITED STATES, January 22, 2025 /⁨EINPresswire.com⁩/ -- Unrattled Company …

Distribution channels: Aviation & Aerospace Industry, Consumer Goods ...

Published on January 22, 2025 - 15:30 GMT

Mobley Announces New Album 'We Do Not Fear Ruins' Out April 23; Shares New Single 'No Exit'

Indie Singer/Songwriter Mobley Announces New Album We Do Not Fear Ruins" Out April 23; Shares New Single & Video "No Exit" NEW YORK, NY, UNITED STATES, January 22, 2025 /⁨EINPresswire.com⁩/ -- Today, Austin-based writer, …

Distribution channels: Music Industry ...
Published on January 23, 2025 - 02:35 GMT

Disc Medicine Announces Pricing of $225.5 Million Upsized Public Offering of Common Stock and Pre-Funded Warrants

WATERTOWN, Mass., Jan. 22, 2025 (GLOBE NEWSWIRE) -- Disc Medicine, Inc. (NASDAQ: IRON) (Disc), a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel treatments for patients suffering from serious …

Distribution channels: Banking, Finance & Investment Industry, Technology ...
Published on January 22, 2025 - 18:45 GMT

Delayed Compliance Stalls 70% of Nutraceutical Firms - Green Jeeva Launches B2B E-commerce Platform

Green Jeeva's B2B e-commerce platform streamlines procurement, boosts efficiency, and ensures regulatory adherence HENDERSON, NV, UNITED STATES, January 22, 2025 /⁨EINPresswire.com⁩/ -- The nutraceutical industry faces significant challenges …

Distribution channels: Food & Beverage Industry ...
Published on January 23, 2025 - 04:05 GMT

PRESS RELEASE – COMPANIES SELLING ELECTRONIC EQUIPMENT ILLEGALLY IN SAMOA

It has come to my attention that some of the companies are selling electronic equipment illegally in Samoa. Such equipment includes mobile phones, walkie talkie, laptop, drone, etc. All equipment that emits and receive frequency signals have to be type …

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Published on January 23, 2025 - 06:00 GMT

AGII Expands Smart Contract Capabilities with Advanced Predictive AI Models

Advanced AI technology enables smarter, more adaptive smart contracts for the evolving Web3 ecosystem. SINGAPORE, SINGAPORE, SINGAPORE, January 23, 2025 /⁨EINPresswire.com⁩/ -- AGII, a trailblazing AI-powered Web3 platform, has unveiled its latest …

Distribution channels: Banking, Finance & Investment Industry, Business & Economy ...
Published on January 23, 2025 - 05:29 GMT

Mopeka and Metsa Tanks Partnership Pairs Underground Propane Tank Safety and Longevity With Tank-and-Cathodic Monitoring

Advanced Tank Technology Promises More Longevity, Reduced Operational Burden, and Better Customer Safety in an Easier-to-Maintain Tank-and-Monitor Package NEW BRAUNFELS, TX, UNITED STATES, January 23, 2025 /⁨EINPresswire.com⁩/ -- Mopeka, a global …

Distribution channels: Agriculture, Farming & Forestry Industry, Companies ...
Published on January 23, 2025 - 05:28 GMT

3-Time Inc. 500 Award-Winning Entrepreneur Jon Flatt Expands Business Accelerator The Guardian CEO to Louisiana

LAFAYETTE, LA, UNITED STATES, January 23, 2025 /⁨EINPresswire.com⁩/ -- Jon Flatt, a Lafayette native and accomplished entrepreneur, is pleased to announce he is bringing his latest business venture, The Guardian CEO, to Louisiana. Flatt is …

Distribution channels: Banking, Finance & Investment Industry, Business & Economy ...
Published on January 23, 2025 - 05:26 GMT

The Guardian CEO Supports Startups in Achieving $50M Valuations Led by Three-Time Inc. 500 Winner Jon Flatt

AUSTIN, TX, UNITED STATES, January 23, 2025 /⁨EINPresswire.com⁩/ -- The Guardian CEO, a business accelerator led by Jon Flatt, a three-time Inc. 500 and two-time Lumiere Award-winning CEO, is pleased to announce it is providing startups and small …

Distribution channels: Banking, Finance & Investment Industry, Business & Economy ...
Published on January 23, 2025 - 03:30 GMT

Medsynaptic Enters the Field of Artificial Intelligence with the Launch of AI for X-Ray & AI-Powered Workflows in PACS

PUNE, MAHARASHTRA, INDIA, January 23, 2025 /⁨EINPresswire.com⁩/ -- Medsynaptic Pvt. Ltd., a pioneer in RIS-PACS, Teleradiology and Healthcare Imaging Solutions, proudly announces its foray into the field of Artificial Intelligence (AI) with the …

Distribution channels: Banking, Finance & Investment Industry, Business & Economy ...
Published on January 23, 2025 - 00:45 GMT

UnifyCloud Announces CloudAtlas AI Guardian: A Complete Solution for Responsible AI Integration, Security and Governance

UnifyCloud launches CloudAtlas AI Guardian to enable enterprises to innovate responsibly while ensuring ethical AI governance, security and compliance. REDMOND, WA, UNITED STATES, January 22, 2025 /⁨EINPresswire.com⁩/ -- UnifyCloud, a leading …

Distribution channels: Automotive Industry, Aviation & Aerospace Industry ...
Published on January 23, 2025 - 00:20 GMT

advancreative Leads SEO Services with Creative Programs for the Top 2025 SEO Trends

advancreative, a leader in creative SEO solutions, is helping businesses stay ahead with innovative programs designed around the top SEO trends for 2025. AKRON, OH, UNITED STATES, January 22, 2025 /⁨EINPresswire.com⁩/ -- advancreative, a leader in …

Distribution channels: Book Publishing Industry, Companies ...
Published on January 23, 2025 - 00:00 GMT

Greg Sobo Named World's Eminent Leader in Injury Law, 2024

Gregory Sobo, Esq., Founder and CEO of Sobo & Sobo, was named “World’s Eminent Leader in Injury Law, 2024" by global industry review organization World Leaders. NEW YORK, NY, UNITED STATES, January 22, 2025 /⁨EINPresswire.com⁩/ -- Greg …

Distribution channels: Business & Economy, Companies ...
Published on January 23, 2025 - 00:00 GMT

Gold Star Plumbing & Drain Honored with Prestigious BBB Torch Award for Ethics

The BBB Torch Award for Ethics was awarded to Gold Star Plumbing & Drain, affirming its dedication to ethical business standards. TEMPE, AZ, UNITED STATES, January 22, 2025 /⁨EINPresswire.com⁩/ -- Gold Star Plumbing & Drain has been …

Distribution channels: Business & Economy, Companies ...
Published on January 23, 2025 - 00:00 GMT

Broadgate Strengthens its Presence in Southeast Asia with New Office in Jakarta, Indonesia

JAKARTA, INDONESIA, January 23, 2025 /⁨EINPresswire.com⁩/ -- We are pleased to announce the opening of our new office in Jakarta, Indonesia. This strategic expansion marks a significant milestone in Broadgate’s commitment to offering top-tier …

Distribution channels: Banking, Finance & Investment Industry, Companies ...
Published on January 23, 2025 - 00:00 GMT

Growing Pediatric Vaccination Awareness Drives Market Growth: Key Driver Transformation in the Ambirix Market 2025

Updated 2025 Market Reports Released: Trends, Forecasts to 2034 – Early Purchase Your Competitive Edge Today! LONDON, GREATER LONDON , UNITED KINGDOM, January 23, 2025 /⁨EINPresswire.com⁩/ -- What's propelling the growth of the Ambirix market …

Distribution channels: Business & Economy, Companies ...
Published on January 22, 2025 - 23:00 GMT

Dov Hertz Shares Commercial Real Estate Development Insights on Recent Podcast

Dov Hertz of DH Property Holdings Shares Commercial Real Estate Development Insights on NEREJ NYREJ Podcast NEW YORK, NY, UNITED STATES, January 22, 2025 /⁨EINPresswire.com⁩/ -- Dov Hertz, founder of DH Property Holdings, recently appeared on Rick …

Distribution channels: Business & Economy, Companies ...
Published on January 22, 2025 - 22:56 GMT

Kevin Harrington Debuts A New Series That Unveils the Secrets to Crafting Winning Pitches on Inside Success Network

FL, UNITED STATES, January 22, 2025 /⁨EINPresswire.com⁩/ -- Inside Success Network is thrilled to announce the premiere of Pitch Your Way to the Top, a dynamic new series hosted by business mogul Kevin Harrington. Known as a Shark Tank pioneer and …

Distribution channels: Business & Economy, Companies ...
Published on January 22, 2025 - 22:15 GMT

Ai Marketing Pioneer Mike Koenigs to Reveal Breakthrough Business Automation Strategies in Exclusive Webinar

How Ai marketing automation can transform your business: 4-month projects done in 4 hours, predictable lead generation, and customer acquisition on autopilot SAN DIEGO, CA, UNITED STATES, January 22, 2025 /⁨EINPresswire.com⁩/ -- At the dawn of …

Distribution channels: Business & Economy, Companies ...
Published on January 22, 2025 - 21:30 GMT

Top Growth Driver in the Aldurazyme Market 2025: Increase In Healthcare Expenditure Driving Market Growth

Aldurazyme Global Market Report 2025 – Market Size, Trends, And Global Forecast 2025-2034 LONDON, GREATER LONDON, UNITED KINGDOM, January 22, 2025 /⁨EINPresswire.com⁩/ -- Updated 2025 Market Reports Released: Trends, Forecasts to 2034 – Early …

Distribution channels: Business & Economy, Companies ...
Published on January 22, 2025 - 21:30 GMT

Global Bayrho D Market Outlook 2025-2034: Growth Drivers, Share, And Trends

Bayrho D Global Market Report 2025 – Market Size, Trends, And Global Forecast 2025-2034 LONDON, GREATER LONDON, UNITED KINGDOM, January 22, 2025 /⁨EINPresswire.com⁩/ -- Updated 2025 Market Reports Released: Trends, Forecasts to 2034 – Early …

Distribution channels: Business & Economy, Companies ...
Published on January 22, 2025 - 20:12 GMT

New Strategies Bridge a Gap Between Sports Passion & Business Success

Bridging passion and profit, Jessy Rodriguez-Melendez’s new program empowers youth sports businesses to thrive while uplifting their communities. YONKERS, NY, UNITED STATES, January 22, 2025 /⁨EINPresswire.com⁩/ -- Business strategist and youth …

Distribution channels: Companies, Education ...
Published on January 22, 2025 - 20:04 GMT

Almeta Slater-Rogers Joins Legacy Makers TV to Share Innovations in Legacy Preservation

FL, UNITED STATES, January 22, 2025 /⁨EINPresswire.com⁩/ -- Almeta Slater-Rogers, founder and CEO of UnSpoken Memories, will appear on Legacy Makers TV. The show features inspiring leaders like Carmen Electra and Russell Brunson, offering audiences …

Distribution channels: Business & Economy, Companies ...
Published on January 22, 2025 - 19:54 GMT

Reatta Hall Joins Legacy Makers TV to Redefine Vegan Dining and Community Leadership

FL, UNITED STATES, January 22, 2025 /⁨EINPresswire.com⁩/ -- Reatta Hall, franchise owner of Slutty Vegan Birmingham, will appear on Legacy Makers TV. The show features inspiring leaders like Carmen Electra and Russell Brunson, offering audiences …

Distribution channels: Business & Economy, Companies ...
Published on January 22, 2025 - 19:53 GMT

Matthew Geiger Joins Legacy Makers TV to Share Lessons in Culinary Entrepreneurship

FL, UNITED STATES, January 22, 2025 /⁨EINPresswire.com⁩/ -- Matthew Geiger, founder of Savour First Choice Catering and Savour Coffee, will appear on Legacy Makers TV. The show features inspiring leaders like Carmen Electra and Russell Brunson, …

Distribution channels: Business & Economy, Companies ...