Tigulixostat Alleviates Hyperuricemic Nephropathy by Promoting M2 Macrophage Polarization
Introduction Urate is the final metabolite in purine metabolism, with xanthine oxidase (XO) playing a crucial role in the production of uric acid by converting hypoxanthine to xanthine and subsequently to uric acid.1,2 Elevated serum uric acid (SUA) levels …