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Published on Nov 12, 2024

Parvalbumin interneuron ErbB4 controls ongoing network oscillations and olfactory behaviors in mice

Discriminating chemical cues in the environment is not only necessary for evaluating potential threats but also influences cognitive and emotional behaviors. The olfactory system dynamically adjusts its sensitivity to odors with changes in the environment …

Source: eLife - Label Pending
Published on Nov 7, 2024

Global Microscope Market Size Expected to Reach $1.64 Billion by 2027, Growing at 3.2% CAGR

WILMINGTON, NEW CASTLE, DE, UNITED STATES, November 7, 2024 /⁨EINPresswire.com⁩/ -- Allied Market Research published an exclusive report, titled, "Microscope Market Size, Share, Competitive Landscape and Trend Analysis Report by Type and End …

Distribution channels: Electronics Industry, Technology ...
Published on Nov 12, 2024

EVIDENT Announces 5th Annual Image of the Year Award Winners

Igor Siwanowicz of the United States was selected as the global winner for his striking cross-section image of a Cosmic Orange Mexican aster flower that vividly depicts pollen grains maturing inside anthers. Beauty of cosmic proportions found in …

Source: The Korea Bizwire - Center-right
Published on Nov 12, 2024

Endophilin A1 facilitates organization of the GABAergic postsynaptic machinery to maintain excitation-inhibition balance

The excitatory and inhibitory synaptic activities of neural circuits are tightly orchestrated in the central nervous system (Sakimoto et al., 2021). The imbalance between excitatory and inhibitory neuronal activity is implicated in many neurological and …

Source: eLife - Label Pending
Published on Nov 12, 2024

Mistargeted retinal axons form synaptically segregated subcircuits in the visual thalamus of albino mice

Activity dependent synaptic remodeling is a process in which patterns of neuron depolarization and synaptic transmission determine whether a given synapse will be maintained, enhanced, or eliminated (Katz and Shatz 1996; J. W. Lichtman and Colman 2000; …

Source: eLife - Label Pending
Published on Nov 11, 2024

Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue ...

Overnutrition and obesity are closely associated with insulin resistance which serves as a common precursor to type 2 diabetes, cardiovascular diseases, non-alcoholic fatty liver disease, and other metabolic disorders. Under chronic energy overload, …

Source: eLife - Label Pending
Published on Nov 11, 2024

Dextran-Graft-Polyacrylamide/Zinc Oxide Nanoparticles Inhibit of Cancer Cells in vitro and in vivo

Introduction The last few decades have witnessed significant advances in nanotechnology. The organization of materials into nanoscale structures noticeably changes their properties. Nanosize-mediated characteristics allow nanoparticles to interact with …

Source: Dove Medical Press - Neutral
Published on Nov 8, 2024

BEHAV3D Tumor Profiler to map heterogeneous cancer cell behavior in the tumor microenvironment

Cancer is a complex disease driven by a sequence of genetic and microenvironmental changes. As a result, tumors comprise many different cell populations that are in constant evolution1. This tumor heterogeneity has important biological and clinical …

Source: eLife - Label Pending
Published on Nov 8, 2024

Multiple Functions of Cerebello-Thalamic Neurons in Learning and Offline Consolidation of a Motor Skill in mice

Learning to execute and automatize certain actions is essential for survival and, indeed, animals have the ability to learn complex patterns of movement with great accuracy to improve the outcomes of their actions (Krakauer, Hadjiosif et al. 2019). Two …

Source: eLife - Label Pending
Published on Nov 9, 2024

PM2.5 Promotes Macrophage-Mediated Inflammatory Response Through Airway Epithelial Cell-Derived Exosomal miR-155-5p

Introduction Airway inflammation is the major driver of chronic obstructive pulmonary disease (COPD) and asthma. Airway epithelial cells (AECs) and alveolar Mφ play a vital role in airway inflammation. AECs serve as the primary barrier against inhaled …

Source: Dove Medical Press - Neutral
Published on Nov 8, 2024

Acute Activation of Genes Through Transcriptional Condensates Impact Non-target Genes in a Chromatin Domain

Acute transcriptional activation of ligand-induced genes drive downstream signalling response. Similar to development-specific genes, signalling induced genes are also driven by enhancers (Hah et al., 2013; Li et al., 2013; Liu et al., 2014; Uyehara & …

Source: eLife - Label Pending
Published on Nov 7, 2024

The Rab7-Epg5 and Rab39-ema modules cooperately position autophagosomes for efficient lysosomal fusions

Macroautophagy is an essential self-degradation pathway in eukaryotic cells, during which double-membrane-bound autophagosomes transport materials to lysosomes for degradation (Parzych & Klionsky, 2014). Defects in autophagy are associated with …

Source: eLife - Label Pending
Published on Nov 7, 2024

Parallel mechanisms signal a hierarchy of sequence structure violations in the auditory cortex

The ability to predict incoming sensory inputs at different timescales is a key cognitive function both in humans and animals (Dehaene et al., 2015; Friston, 2005; Keller and Mrsic-Flogel, 2018). Predictions are classically revealed by specific responses …

Source: eLife - Label Pending
Published on Nov 8, 2024

Nasal mRNA Nanovaccine with Key Activators of Dendritic and MAIT Cells for Effective Against Lung Tumor Metastasis in ...

Introduction The majority of cancer-related fatalities are caused by the spread of cancer cells to distant parts of the body rather than the initial tumor. The incidence of lung metastasis in cancer patients ranges from 20% to 54%, making it a major …

Source: Dove Medical Press - Neutral
Published on Nov 7, 2024

pH-Responsive Charge-Reversal Smart Nanoparticles for Co-Delivery of Mitoxantrone and Copper Ions to Enhance Breast ...

Introduction Chemotherapy is widely used to treat breast cancer in clinical practice, but the chemoresistance and adverse effects of poor selectivity on cancer tissue severely limit their clinical application.1 Developed nanomedicines can realize tumor …

Source: Dove Medical Press - Neutral

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Published on November 12, 2024 - 13:15 GMT

Biotricity to Host Fourth Quarter Fiscal Year 2024 Financial Results and Business Update Call on November 15th

Company to announce the best financial results thus far, showing improvements in Margins, Operational Efficiency, and a shift to positive Adjusted EBITDA REDWOOD CITY, CA, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- Biotricity Inc. ( …

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Published on November 12, 2024 - 21:05 GMT

Artiva Biotherapeutics Reports Third Quarter 2024 Financial Results and Recent Business Highlights

Expanded Board of Directors with appointment of Dr. Alison Moore bringing cell therapy and manufacturing expertise to advance AlloNK® in autoimmune diseases Initial data for AlloNK® in autoimmune indications expected H1 2025 Robust balance sheet with cash, …

Distribution channels: Media, Advertising & PR, Technology ...

Published on November 12, 2024 - 21:09 GMT

SI-BONE, Inc. Reports Financial Results for the Third Quarter 2024 and Updates Guidance

SANTA CLARA, Calif., Nov. 12, 2024 (GLOBE NEWSWIRE) -- SI-BONE, Inc. (Nasdaq:SIBN), a medical device company dedicated to solving sacropelvic disorders, today reported financial results for the quarter ended September 30, 2024. Third Quarter 2024 Financial …

Distribution channels: Business & Economy, Healthcare & Pharmaceuticals Industry ...
Published on November 12, 2024 - 21:05 GMT

Bolt Biotherapeutics Reports Third Quarter 2024 Financial Results and Provides Business Update

Advanced to the highest dose level in the Phase 1 dose-escalation clinical study of BDC-3042 in patients with advanced cancers Presented updated preclinical activity of BDC-4182 and key learnings from Phase 1 dose-escalation trial of BDC-1001 at the SITC …

Distribution channels: Business & Economy, Healthcare & Pharmaceuticals Industry ...

Published on November 12, 2024 - 21:01 GMT

Fate Therapeutics Reports Third Quarter 2024 Financial Results and Business Updates

Initial Clinical Data from Phase 1 Autoimmunity Study of FT819 1XX CAR T-cell Product Candidate to be Presented in 4Q24; Second Treatment Arm Adding FT819 to Maintenance Therapy without Conditioning Chemotherapy Opened for Enrollment FT522 Multi-indication …

Distribution channels: Business & Economy, Healthcare & Pharmaceuticals Industry ...
Published on November 12, 2024 - 21:15 GMT

Kodak Reports Third-Quarter 2024 Financial Results

ROCHESTER, N.Y., Nov. 12, 2024 (GLOBE NEWSWIRE) -- Eastman Kodak Company (NYSE: KODK) today reported financial results for the third quarter 2024. Third-quarter 2024 highlights include: Consolidated revenues of $261 million, compared with $269 million for …

Distribution channels: Business & Economy, Electronics Industry ...
Published on November 12, 2024 - 21:05 GMT

CARGO Therapeutics Reports Third Quarter 2024 Financial Results and Provides Business Update

- 57 patients dosed in the potentially pivotal Phase 2 clinical study, FIRCE-1 of firicabtagene autoleucel (firi-cel); on track for interim analysis in 1H25 - - CRG-023 pre-clinical data to be presented at ASH 2024; IND submission anticipated Q1’25 with …

Distribution channels: Business & Economy ...
Published on November 12, 2024 - 21:05 GMT

Fractyl Health Reports Third Quarter 2024 Financial Results and Provides Business Updates

REMAIN-1 weight maintenance pivotal study enrollment progressing rapidly; mid-point data analysis expected in Q2 2025 Anticipate reporting data from REVEAL-1 open-label cohort beginning in Q4 2024 Topline data from REVITALIZE-1 pivotal study expected in …

Distribution channels: Business & Economy, Healthcare & Pharmaceuticals Industry ...

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Published on November 13, 2024 - 00:38 GMT

California Closets Virginia Beach Hosts First CVBIA Member Mingle

California Closets Designers Build Bridges and Make Connections in the Virginia Beach Home Development Community VIRGINIA BEACH, VA, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- On October 3, 2024, California Closets proudly hosted its …

Distribution channels: Business & Economy, Companies ...
Published on November 13, 2024 - 00:27 GMT

Community Unites to Help Fill-A-Bag for SnowCap Community Charities

Last year's Fill-A-Bag drive exceeded all expectations, doubling cash contributions and collecting thousands of pounds of food, clothing, and pet supplies. GRESHAM, OR, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- With the kick-off …

Distribution channels: Automotive Industry, Banking, Finance & Investment Industry ...
Published on November 13, 2024 - 00:00 GMT

Global Loyalty Management Market To Reach $20.3 Billion By 2028 With A Growth Rate Of 16.6%

The Business Research Company has updated its global market reports with latest data for 2024 and projections up to 2033 LONDON, GREATER LONDON , UNITED KINGDOM, November 13, 2024 /⁨EINPresswire.com⁩/ -- The Business Research Company’s Early Year- …

Distribution channels: Banking, Finance & Investment Industry, Business & Economy ...
Published on November 12, 2024 - 23:52 GMT

Why Dr. Tyson Cobb Believes Now Is the Best Time to Invest in Commercial Real Estate

Strategic Insights from Dr. Tyson Cobb on Capitalizing in Today’s Commercial Real Estate Landscape BETTENDORF, IA, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- As we navigate one of the most turbulent periods in recent memory for …

Distribution channels: Companies, Education ...
Published on November 12, 2024 - 23:33 GMT

Growth Friday Expands to Miami: Affordable Digital Marketing Solutions for Small Businesses

Supporting Miami's Small and Medium Businesses with Cost-Effective, High-Impact Marketing MIAMI, FL, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- Growth Friday, a premier digital marketing firm specializing in small business …

Distribution channels: Automotive Industry, Companies ...
Published on November 12, 2024 - 23:20 GMT

Outbuild Secures $11 Million in Series A Funding

A Key Step in Supporting On-Time Completion for Construction Projects Globally SAN FRANCISCO, CA, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- Outbuild, a construction scheduling and planning software company, today announced it has …

Distribution channels: Building & Construction Industry, Business & Economy ...
Published on November 12, 2024 - 23:17 GMT

Creative Repute Seeks Passionate Account Manager to Join an Inclusive, People-First Team

Creative Repute is hiring an Account Manager with an entrepreneurial spirit to foster client success in a supportive, inclusive environment. PHILADELPHIA, PA, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- Creative Repute, a values- …

Distribution channels: Business & Economy, Companies ...
Published on November 12, 2024 - 23:03 GMT

SkillsAware announces its official launch and launch of AI-powered skills recognition service and consultancy

SkillsAware launches today, in collaboration with SkillsIQ, Edalex, and Dr. Mark Keough, delivering AI-powered skills recognition service and consultancy. SYDNEY, NEW SOUTH WALES, AUSTRALIA, November 12, 2024 /⁨EINPresswire.com⁩/ -- SkillsAware, …

Distribution channels: Business & Economy, Companies ...
Published on November 12, 2024 - 23:02 GMT

Natchez Workforce Development Announces New Website

NATCHEZ, MS, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- Natchez Workforce Development is excited to announce the launch of its new website. The website is part of its ongoing mission to assist in the creation, promotion, and …

Distribution channels: Business & Economy, Companies ...
Published on November 12, 2024 - 23:01 GMT

PSMJ Resources Celebrates 50th Anniversary at Gillette Stadium’s 50-Yard Line

PSMJ marks five decades of advancing AEC performance with a milestone event. NEWTON, MA, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- PSMJ Resources, a global leader in business consulting and training for architecture, engineering, …

Distribution channels: Business & Economy, Companies ...
Published on November 12, 2024 - 22:54 GMT

CAD eksperti tiekas 26. novembrī Rīgā pasākumā PLM Innovation Day 2024

Reģistrēties ir iespējams PLM Group Latvia tīmekļvietnē. RIGA, LATVIA, November 13, 2024 /⁨EINPresswire.com⁩/ -- PLM Group arī šogad rīko lielāko produktu izstrādes un CAD dizaina speciālistu pasākumu – PLM Innovation Day –, kas notiks 2024. gada …

Distribution channels: Automotive Industry, Companies ...
Published on November 12, 2024 - 22:53 GMT

1909 Annual Gala Supports Next Generation of Entrepreneurs in Palm Beach County

West Palm Beach Non-Profit Organization Serves Entrepreneurs and Small Businesses with Affordable Workspace and Business Education Programs WEST PALM BEACH , FL, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- 1909, a non-profit …

Distribution channels: Business & Economy, Companies ...
Published on November 12, 2024 - 22:51 GMT

Amalfi Jets Announces the Launch of the Amalfi Enterprise Program a New Travel Solution for Businesses

Amalfi Jets, a premier private jet charter company, is excited to announce the launch of its highly anticipated Amalfi Enterprise Program. LOS ANGELES, CA, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- Amalfi Jets, a premier private jet …

Distribution channels: Aviation & Aerospace Industry, Business & Economy ...
Published on November 12, 2024 - 22:30 GMT

DreamHome Remodeling & Builders Brings Comprehensive Remodeling Services to the California Bay Area

DreamHome Remodeling & Builders, based in San Jose, California, provides remodeling services for residential and commercial projects. SAN JOSE, CA, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- DreamHome Remodeling & Builders is …

Distribution channels: Building & Construction Industry, Companies ...
Published on November 12, 2024 - 22:13 GMT

Mindatorium Secures Streaming Rights to 'The Man Who Met GOD' and Kicks Off Promotional Push in New York’s Times Square

Highly acclaimed documentary is now available for viewing exclusively on company’s global streaming platform BEVERLY HILLS, CA, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- Mindatorium, Inc, a Beverly Hills based multi-media …

Distribution channels: Amusement, Gaming & Casino, Banking, Finance & Investment Industry ...
Published on November 12, 2024 - 22:12 GMT

Ernesto Illy International Coffee Award 2024: The Future of Coffee Takes Center Stage at the United Nations.

Top Industry Experts in New York to Tackle Coffee's Climate Crisis and Discuss Regenerative Agriculture Solutions Through Public-Private Collaboration. NEW YORK, NY, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- In a world facing …

Distribution channels: Agriculture, Farming & Forestry Industry, Companies ...
Published on November 12, 2024 - 22:03 GMT

Ichor Life Sciences Inc. Announces the Opening of Phase I-IV Clinical Trial Facility in Syracuse, NY

SYRACUSE, NY, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- Ichor Research is the newest addition to the Ichor umbrella, adding the execution of Phase I-IV human clinical trials to Ichor’s end-to-end service model. Ichor Life …

Distribution channels: Business & Economy, Companies ...
Published on November 12, 2024 - 22:00 GMT

Ed Andrews Career Coaching Launches New Resume Building Service

Ed Andrews introduces a resume building service. BRISBANE, QLD, AUSTRALIA, November 13, 2024 /⁨EINPresswire.com⁩/ -- Ed Andrews Career Coaching is excited to announce the launch of its new Resume Building Service, designed to help clients create …

Distribution channels: Companies, Technology ...
Published on November 12, 2024 - 21:44 GMT

Adventure Racing World Series Supports IARA and Campaign against World Obstacle and World Pentathlon

The ARWS calls on World Pentathlon (UIPM) to withdraw it's proposal to govern adventure racing, which is against the wishes of those in the sport. BENTONVILLE, AR, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- The Adventure Racing …

Distribution channels: Companies, Environment ...
Published on November 12, 2024 - 21:12 GMT

ISSIP Elects Haluk Demirkan Vice President for 2025

Milgard Endowed Professor at Univ of WA Tacoma, Cognitive Science Lead at Amazon, and ISSIP Co-Founder will focus on sustainable growth for organization SANTA CLARA, CA, UNITED STATES, November 12, 2024 /⁨EINPresswire.com⁩/ -- The International …

Distribution channels: Companies, IT Industry ...