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Published on Dec 11, 2024

Demystifying Ligand Pharmaceuticals: Insights From 10 Analyst Reviews

In the latest quarter, 10 analysts provided ratings for Ligand Pharmaceuticals LGND, showcasing a mix of bullish and bearish perspectives. Summarizing their recent assessments, the table below illustrates the evolving sentiments in the past 30 days and …

Source: Benzinga - Neutral
Published on 17:02 GMT

LC–MS-Based Proteomics for Protein Biomarker Quantification for Both Prognosis and Diagnosis in the Clinical Setting

Biomarkers play a significant role in evaluating disease risk and treatment by acting as indicators of biological processes as well as pharmacological reactions to therapy. Candidate protein biomarkers are highly promising, specific biomarkers. These …

Source: LCGC International - Label Pending
Published on 18:51 GMT

Identification of Macrophage-Related Biomarkers for Abdominal Aortic Aneurysm Through Combined Single-Cell Sequencing ...

Introduction Abdominal aortic aneurysm (AAA) is a cardiovascular condition characterized by a pathological dilation of the aorta exceeding 50%, which can pose a major risk of aortic rupture and hemorrhage.1 Notably, AAA is often clinically silent until …

Source: Dove Medical Press - Neutral
Published on Dec 11, 2024

Indian Shot (Canna Indica L). Leaves Provide Valuable Insights into the Management of Inflammation and Other Associated ...

Introduction The search for new therapeutic agents has increasingly led researchers to explore bioactive compounds derived from natural sources, which present a complex and vast network of chemical diversity across various organisms, offering an extensive …

Source: Dove Medical Press - Neutral
Published on Dec 10, 2024

Zuojin Pill Alleviates Precancerous Lesions of Gastric Cancer by Modulating the MEK/ERK/c-Myc Pathway: An Integrated ...

Introduction Gastric cancer (GC) is the fifth most common malignancy worldwide and the fourth leading cause of cancer-related deaths.1 Before GC onset, precancerous lesions of gastric cancer (PLGC) often develop in the gastric mucosa, which include chronic …

Source: Dove Medical Press - Neutral
Published on Dec 10, 2024

Unveiling the Therapeutic Potential of Berberine in Rheumatoid Arthritis: A Comprehensive Study of Network Pharmacology, ...

Introduction Rheumatoid arthritis (RA) is an autoimmune disorder distinguished by persistent synovitis, leading to localized bone and cartilage damage, along with various systemic manifestations. The quality of life for individuals with RA is significantly …

Source: Dove Medical Press - Neutral
Published on Dec 5, 2024

Leveraging Advancements in Bioanalytical Testing

It is well-known that developing a drug from the discovery through to commercialization is a costly endeavor, with market analysis showing that the average R&D cost to develop an asset for 2022–2023 was $2.3 billion (1). However, many drugs do not make …

Source: Pharmaceutical Technology - Neutral
Published on 10:58 GMT

New targeted therapies show promise in lung cancer treatment

Recent advancements in targeted therapies and immunotherapies are transforming lung cancer treatment. Discover how these innovations are improving outcomes and providing hope for patients. Lung cancer is the most commonly diagnosed cancer worldwide, …

Source: Drug Target Review - Neutral
Published on Dec 12, 2024

Profile of Ofatumumab in the Treatment of Multiple Sclerosis: Design, Development and Place in Therapy

Introduction Multiple sclerosis (MS) is an autoimmune pathology characterized by demyelination within the central nervous system (CNS) encompasses inflammatory and neurodegenerative processes. Approximately 2.8 million individuals worldwide are affected by …

Source: Dove Medical Press - Neutral
Published on Dec 11, 2024

Unlocking the Mechanisms of Hidradenitis Suppurativa: Inflammation and miRNA Insights

Introduction The Complex Dynamics of HS: Incidence, Influences, and Implications Painful nodules, abscesses, and sinus tracts characterize hidradenitis suppurativa (HS), a chronic inflammatory skin condition. Historically known by various names such as …

Source: Dove Medical Press - Neutral
Published on Dec 11, 2024

Physicochemical Property Effects on Immune Modulating Polymeric Nanoparticles: Potential Applications in Spinal Cord ...

Introduction Spinal cord injury (SCI) results in loss of sensation, movement, and autonomic functions of the body below the level of injury.1,2 The time course of SCI can be divided into two phases: the primary injury and prolonged secondary injury.3,4 The …

Source: Dove Medical Press - Neutral
Published on Dec 11, 2024

Advances in the Study of Denosumab Treatment for Osteoporosis and Sarcopenia in the Chinese Middle-Aged and Elderly ...

Introduction According to the 2020 national census by the National Bureau of Statistics of China, nearly 270 million people in China are aged 60 and above, comprising 18.7% of the total population, while those aged 65 and above number over 190 million, or …

Source: Dove Medical Press - Neutral
Published on Dec 10, 2024

Portulaca Oleracea L. as a Potential Therapeutic Drug Intervention in Ulcerative Colitis: Mechanisms of Action and ...

Introduction Ulcerative colitis (UC) is a lifelong chronic non-specific inflammatory bowel disease (IBD), characterized by bloody mucous stools, abdominal pain, diarrhea, and tenesmus. UC lesions primarily occur in the colon and rectum and are limited to …

Source: Dove Medical Press - Neutral
Published on Dec 9, 2024

25 techbio leaders that shaped the AI-biology convergence in 2024

But there is more to the story. Despite these headwinds, the techbio sector continues to attract significant investment and drive innovation. 2024 saw the launch of Xaira, a techbio with the financial backing of over $1 billion. At the helm of the firm is …

Source: R&D Magazine - Label Pending
Published on Dec 10, 2024

Scoping Review: The Effects of Interrupted Onabotulinumtoxin A Treatment for Chronic Migraine Prevention During the ...

Introduction The coronavirus (COVID-19) pandemic was unprecedented in its impact on the medical community throughout the world. By March 2020, the majority of medical centers and healthcare institutions in the United States (US) had begun significantly …

Source: Dove Medical Press - Neutral
Published on Dec 9, 2024

Sonnet BioTherapeutics Announces Topline Safety Data Following Successful Completion of SON-1010 Monotherapy Dose ...

The maximum tolerated dose (MTD) of SON-1010 was set at 1200 ng/kg, without dose-limiting toxicity or evidence of cytokine release syndrome at any dose level Stable disease (SD) at four months post-initiation of dosing was seen in 10 of 21 (48%) …

Distribution channels: Technology ...
Published on Dec 10, 2024

Discover Mutational Differences Between Lung Adenocarcinoma and Lung Squamous Cell Carcinoma and Search for More ...

Introduction Lung cancer is a severe malignant tumor and remains one of the leading causes of cancer-related deaths globally.1 The predominant type of lung cancer is non-small cell lung cancer (NSCLC), constituting approximately 85% of all cases. NSCLC is …

Source: Dove Medical Press - Neutral
Published on Dec 9, 2024

Identification of Candidate Hub Genes and Drug Targets for Cholangiocarcinoma via Juhua (Chrysanthemum Morifolium) ...

Introduction Cholangiocarcinoma (CHOL) is a rare but aggressive malignancy originating from the epithelial cells lining the bile ducts. Its low incidence, diverse clinical presentations, and lack of early diagnostic markers contribute to significant …

Source: Dove Medical Press - Neutral
Published on Dec 9, 2024

Fucosterol and Fucoxanthin Enhance Dentin Collagen Stability and Erosion Resistance Through Crosslinking and MMP ...

Introduction Dentin is a hard dental tissue, which contributes to tooth function and health, making its preservation important to oral health outcomes. Despite its hardness, dentin is susceptible to mechanical and chemical challenges, including erosion and …

Source: Dove Medical Press - Neutral

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Published on December 13, 2024 - 18:55 GMT

Thomas & Taylor Search Partners Welcomes Gonzalo Pacanins as President - Executive Talent Solutions for PE/VC Firms

TTSP, a top boutique firm for Executive and Board placements, names Gonzalo Pacanins as President of Executive Talent Solutions for PE/VC firms. DALLAS, TX, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- Thomas & Taylor Search …

Distribution channels: Banking, Finance & Investment Industry ...
Published on December 13, 2024 - 12:59 GMT

France Creator Economy Market Size, and Shares are Likely to Grow at a CAGR Value of 24.2% By 2031

The France creator economy market is expected to reach USD 31,153.8 Mn by 2031, growing at a CAGR of 24.2% from 2024 to 2031. CA, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- The latest report titled "France Creator Economy Market …

Distribution channels: Business & Economy ...

Published on December 13, 2024 - 07:03 GMT

Healthcare Revenue Cycle Management Market Is Booming Worldwide 2024-2031: Athena health, Inc., GE Healthcare

BURLINGAME, CA, UNITED STATES, December 12, 2024 /⁨EINPresswire.com⁩/ -- Latest Report, titled “Healthcare Revenue Cycle Management Market” Trends, Share, Size, Growth, Opportunity and Forecast 2024-2031, by Coherent Market Insights offers a …

Distribution channels: Healthcare & Pharmaceuticals Industry ...
Published on December 13, 2024 - 17:46 GMT

Transaction in Own Shares

Transaction in Own Shares 13 December, 2024 • • • • • • • • • • • • • • • • Shell plc (the ‘Company’) announces that on 13 December 2024 it purchased the following number of Shares for cancellation. Aggregated information on Shares purchased …

Distribution channels: Media, Advertising & PR ...

Published on December 13, 2024 - 15:21 GMT

Southeastern Equipment Company Showcases CASE Construction Equipment with Hands-On Demo Event in Dublin, Ohio

Southeastern Equipment Company recently concluded a, demo event featuring CASE Construction’s Mini Track Loader (MTL) and Small Articulated Loader (SAL) lines. DUBLIN, OH, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- Southeastern …

Distribution channels: Agriculture, Farming & Forestry Industry, Automotive Industry ...
Published on December 13, 2024 - 14:00 GMT

EnWave Reports 2024 Fourth Quarter and Annual 2024 Consolidated Financial Results

VANCOUVER, British Columbia, Dec. 13, 2024 (GLOBE NEWSWIRE) -- EnWave Corporation (TSX-V:ENW | FSE:E4U) (“EnWave”, or the "Company") reported the Company’s consolidated interim financial results for the fourth quarter and fiscal year ended …

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Published on December 13, 2024 - 20:48 GMT

Justice Department Announces Resolution of Criminal and Civil Investigations into McKinsey & Company’s Work with Purdue ...

McKinsey & Company Inc. (McKinsey), a global management consulting firm based in New York, has agreed to pay $650 million to resolve a criminal and civil investigation into the firm’s consulting work with opioids manufacturer Purdue Pharma L.P. (Purdue …

Distribution channels: U.S. Politics
Published on December 13, 2024 - 16:38 GMT

Spacecraft Market Size Will Generate Record Revenue: $11.7 Billion by 2033

The global spacecraft market size was valued at $6.9 billion in 2023, is projected to reach $11.7 billion by 2033, growing at a CAGR of 5.7% from 2024 to 2033. WILMINGTON, NEW CASTLE, DE, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- …

Distribution channels: Aviation & Aerospace Industry, Military Industry ...

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Published on December 13, 2024 - 20:31 GMT

Samson Media’s Introduces Lead-Generating Websites for Franchise Broker Consultants

MONTCLAIR, NJ, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- Samson Media, a leader in digital marketing and web design, is transforming the way franchise consultants attract and engage prospective franchisees. The company is setting a …

Distribution channels: Business & Economy, Companies ...
Published on December 13, 2024 - 20:20 GMT

Changes Ahead in the Master Group Health Environment for PEOs

Level-Funded Health Plans Gain Ground as PEOs Rethink Master Group Health Strategies TAMPA, FL, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- The world of Professional Employer Organizations (PEOs) is no stranger to evolution, and the …

Distribution channels: Business & Economy, Companies ...
Published on December 13, 2024 - 19:42 GMT

KnowVisory Global’s Expert Bookkeeping Services Help US Businesses Stay Financially Sharp and Focused on Growth

WYLIE, TX, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- Managing finances is one of the most critical, yet often overlooked, aspects of running a successful business. KnowVisory Global, a leading US firm specializing in finance and …

Distribution channels: Business & Economy, Companies ...
Published on December 13, 2024 - 18:58 GMT

Caretech and Local Partners Celebrate Veterans with Red, White, and Blue BBQ

A Red, White, and Blue BBQ honored Nebraska veterans with food, games, and fundraising, raising $6,000+ and collecting vital donations for local veterans. OMAHA, NE, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- Caretech, in partnership …

Distribution channels: Companies, Culture, Society & Lifestyle ...
Published on December 13, 2024 - 18:55 GMT

Xraised Interview with Louisa Klouda, CEO & Founder at Fenchurch Legal

LONDON, ENGLAND, UNITED KINGDOM, December 13, 2024 /⁨EINPresswire.com⁩/ -- In a recent exclusive interview with Xraised, Louisa Klouda, the CEO and Founder at Fenchurch Legal, shared insights into the company's innovative approach to litigation …

Distribution channels: Banking, Finance & Investment Industry, Business & Economy ...
Published on December 13, 2024 - 18:53 GMT

Montana West World Launches Buy One Get One 50% Off Sitewide Xmas Promo

This holiday season, Montana West is spreading festive cheer with a sitewide Buy One Get One 50% off deal along with mystery gift boxes. DALLAS, TX, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- Montana West is providing a convenient …

Distribution channels: Companies, Consumer Goods ...
Published on December 13, 2024 - 18:52 GMT

US Ghost Adventures Hosts Toys for Tots Drive This Saturday

Support a Great Cause with Spooky Fun at the Lizzie Borden House and Brick House Inn FALL RIVER, MA, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- This Saturday, December 14, US Ghost Adventures, in partnership with Toys for Tots, is …

Distribution channels: Companies, Culture, Society & Lifestyle ...
Published on December 13, 2024 - 18:39 GMT

Cabo Del Sol Apartments Has Been Acquired By Break of Day Capital

Break of Day Capital Acquires 10th Tucson Property, Expands Multifamily Impact Fund Portfolio with Icon on Midvale, a 136-Unit Value-Add Community. MANHATTAN BEACH, CA, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- Break of Day Capital, …

Distribution channels: Banking, Finance & Investment Industry, Business & Economy ...
Published on December 13, 2024 - 18:22 GMT

Rising Popularity of Wine and Champagne Gift Sets with Tiffany Flutes Marks a Shift in Gifting Trends

Celebrating Special Occasions with Curated Wine and Glassware Combos. WASHINGTON DC, DC, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- The gifting industry has witnessed a notable evolution in recent years, with a growing preference for …

Distribution channels: Business & Economy, Companies ...
Published on December 13, 2024 - 18:00 GMT

Taskade Unveils Public Agent Inbox, Enhanced Agent Tools, and Google Workspace Automations

Taskade enhances project automation with a Public Agent Inbox, customizable AI tools, and seamless Google Workspace integrations. SAN FRANCISCO, CA, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- Taskade, a leader in AI-powered …

Distribution channels: Business & Economy, Companies ...
Published on December 13, 2024 - 18:00 GMT

Amazon Photographer EtherArts Product Photography Offers Low Prices To Small E-commerce Businesses Amidst High Inflation

Amazon photographer EtherArts offers low and reduced pricing to small and medium e-commerce businesses extending its support amidst USA high inflation markets. ATLANTA, GA, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- The Impact of …

Distribution channels: Business & Economy, Companies ...
Published on December 13, 2024 - 17:30 GMT

Xraised Exclusive: Dr. Jason Roop Discusses Groundbreaking Trait-Based Model of Recovery

CAMPBELLSVILLE, KY, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- Xraised had the honor of interviewing Dr. Jason Roop, Founder and CEO of The Center for Trait-Based Transformation, to explore his innovative approach to addiction …

Distribution channels: Companies, Emergency Services ...
Published on December 13, 2024 - 17:29 GMT

Frank Biden: the Importance of COVID-19 Class Action Lawsuits in Pursuit of Justice and Accountability

BOCA RATON, FL, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- Frank Biden, a non-attorney strategist at the Berman Law Group, a Florida based law firm, underscores the significance of COVID-19 2020 class action lawsuit in holding …

Distribution channels: Business & Economy, Companies ...
Published on December 13, 2024 - 17:16 GMT

Arden Nights 2024: How Music and Evertreen’s Tree-Planting Initiative Transformed Nepal’s Ecosystems

LOS ANGELES, CA, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- Evertreen, the platform that makes it easy to plant real trees online, is thrilled to look back on the success of its partnership with Arden Records during Arden Nights 2024. …

Distribution channels: Companies, Energy Industry ...
Published on December 13, 2024 - 17:02 GMT

CASA Of The Eastern Panhandle Welcomes New Class Of Volunteers To Its Community Of Dedicated Advocates

On Thursday, December 12, 2024, CASA of the Eastern Panhandle (CASA-EP) welcomed new volunteer advocates to its dedicated team of volunteers. MARTINSBURG, WV, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- On Thursday, December 12, 2024, …

Distribution channels: Companies, Culture, Society & Lifestyle ...
Published on December 13, 2024 - 17:00 GMT

SaaSify Introduces HubSpot Connector for AWS ACE Co-Sell Automation

Transforming Co-Sell Efficiency for ISVs with AWS ACE Management in HubSpot SEATTLE, WA, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- SaaSify by Spektra Systems, a leading platform dedicated to helping Independent Software Vendors ( …

Distribution channels: Business & Economy, Companies ...
Published on December 13, 2024 - 16:43 GMT

Better Days Treatment Center Now Offers Inpatient Drug Rehab and High End Amenities in a Coastal Setting in California

Anaheim, California – Better Days Treatment Center, a leading detox and rehab facility, is excited to announce that it is now offering inpatient drug rehab with access to high-end amenities to help offer individuals struggling with substance addiction the …

Distribution channels: Business & Economy, Companies ...
Published on December 13, 2024 - 16:43 GMT

Veteran Innovator Steve Zeidman Acquires BarkPass, Expanding Leadership in Pet Licensing and Dog Park Management

Strategic Acquisition Aims to Increase Innovation and Access to Cutting-Edge Solutions for Communities to Support Pets and Their People PHOENIX, AZ, UNITED STATES, December 13, 2024 /⁨EINPresswire.com⁩/ -- Barkpass, a pioneering software company …

Distribution channels: Companies ...
Published on December 13, 2024 - 16:41 GMT

Your IT Department: What Small And Medium Businesses Need to Know About Cybersecurity In 2025

Leicester, East Midlands – Your IT Department, an award-winning provider of outsourced IT support, highlights the importance of robust cybersecurity measures for small and medium businesses, particularly as they navigate the challenges of 2025. The …

Distribution channels: Business & Economy, Companies ...
Published on December 13, 2024 - 16:37 GMT

Dolphin Discovery activities in Isla Mujeres for December

Isla Mujeres comes alive with magic and joy this December with the special activity program Dolphin Discovery has prepared for its visitors. CANCUN, ISLA MUJERES, MEXICO, December 13, 2024 /⁨EINPresswire.com⁩/ -- December is filled with magic and …

Distribution channels: Companies, Culture, Society & Lifestyle ...