New Products: ATMI Launches Disposable Bioreactor

April 23, 2010 (FinancialWire) — ATMI, Inc. (NASDAQ: ATMI) has launched a disposable bioreactor, representing a scalable entry point in its line of mixing and process manufacturing systems for the biopharma and biotech industries.

The introduction took place at INTERPHEX, an annual conference on life sciences manufacturing equipment, production process, and packaging developments.

The Integrity™ PadReactor™ system accommodates volumes ranging from 20 liters to 1,000 liters. The bioreactor is portable along its entire range of volumes and provides features available on larger, stationary units, while offering swifter set-up times, minimal facility requirements, and the economic benefits of single-use technologies over stainless steel systems.

"When customers see this system for the first time, they're surprised by the square tank or the sparger's action in the vessel," said Jeff Craig, ATMI LifeSciences' global director of marketing and business development. "Once they put the PadReactor to use, we consistently hear them talk about its higher cell densities in suspension, higher cell viability on microcarriers, and better overall yields than other single-use bioreactors."

Incorporating key elements of ATMI's industry-leading PadMixer™ technology, the PadReactor system provides enhanced gas exchange, due to its moving sparger. It also achieves low shear mixing due to the vertices of the square tank, which act as natural baffles. These advantages, plus the system's scalability, make it ideal for the production of vaccines, monoclonal antibodies, and other secreted proteins.

Increasing the overall versatility of the Integrity PadReactor system is ATMI's decision to publish its interface standards, enabling this single-use bioreactor to be paired with any controller technology. ATMI can configure the system with integrated control and monitoring technology or, thanks to its open architecture, allow users to purchase it in "plug-and-play" mode: ready for their own choice in technology.

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